A Hidden Foot Melanoma’s Path to The Inguinal Nodes: Diagnostic Pitfalls and Therapeutic Considerations

Authors

Keywords:

Malignant melanoma, Inguinal lymph node metastasis, Lower extremity melanoma, Misdiagnosis

Abstract

Malignant melanoma of the lower limb and foot frequently metastasizes to the inguinal lymph nodes, carrying a poor prognosis akin to other tumors with distant spread. Due to patient unawareness, foot melanomas are often misdiagnosed or undetected, delaying diagnosis. In rare instances, the popliteal fossa serves as the initial site of nodal metastasis, with popliteal metastasis rates in lower extremity melanomas ranging from 0.3% to 7%. Concurrent popliteal and inguinal lymph node metastases are exceptionally uncommon. We report the case of a 67-year-old woman presenting with a right inguinal mass, later diagnosed with metastatic malignant melanoma following surgical excision. Further history revealed a prior excision of a lesion on the right sole of the foot without histopathological analysis, suggesting an undiagnosed primary melanoma. This case underscores the diagnostic challenges of foot melanoma and the rare potential for atypical metastatic patterns.

Downloads

Download data is not yet available.

References

Jemal A, Siegel R, Xu J, Ward E. Cancer statistics, 2010. CA Cancer J Clin. 2010;60(5):277–300.

Piero C, Barberini F, De Giorgi V, Anania G, Santoro A, Bruzzone P, et al. The lymphatic drain of below-knee malignant melanoma: Is the popliteal Fossa a ghost station? Indian J Surg. 2021;83(6):1364–72.

Saida T. Malignant melanoma on the sole: How to detect the early lesions efficiently. Pigment Cell Res. 2000;13(s8):135–9.

Samdariya S, Kumar D, Vishwanathan C, Ahmed I. An unusual case of masquerading malignant melanoma. Clin Cancer Investig J. 2015.

Baumert J, Plewig G, Volkenandt M, Schmid-Wendtner M-H. Factors associated with a high tumour thickness in patients with melanoma. Br J Dermatol. 2007;156(5):938–44.

Costa SR, Horta SHC, Henriques AC. Popliteal lymphadenectomy for treating metastatic melanoma: case report. Sao Paulo Med J. 2008;126(4):232–5.

Wright S, Armeson K, Hill EG, Streck C, Leddy L, Cole D, et al. The role of sentinel lymph node biopsy in select sarcoma patients: a meta-analysis. Am J Surg. 2012;204(4):428–33.

Lhote R, Lambert J, Lejeune J, Gottlieb J, Badaoui A, Battistella M, et al. Sentinel lymph node biopsy in cutaneous squamous cell carcinoma series of 37 cases and systematic review of the literature. Acta Derm Venereol. 2018;98(7):671–6.

Morcos BB, Hashem S, Al-Ahmad F. Popliteal lymph node dissection for metastatic squamous cell carcinoma: a case report of an uncommon procedure for an uncommon presentation. World J Surg Oncol. 2011;9(1):130.

Silberman AW. Malignant melanoma. Practical considerations concerning prophylactic regional lymph node dissection. Ann Surg. 1987;206(2):206–9.

Downloads

Published

13-08-2025

How to Cite

SANKAR, N. ., SINGH, T. P. ., PASI , . D. K. ., SINGH , . J. ., DHAMIJA , . P. ., & KUMAR , . A. . (2025). A Hidden Foot Melanoma’s Path to The Inguinal Nodes: Diagnostic Pitfalls and Therapeutic Considerations. GMC Patiala Journal of Research and Medical Education, 8(01), 41–44. Retrieved from https://jrme.gmcpatiala.edu.in/index.php/j/article/view/202

Issue

Section

Case Report

Most read articles by the same author(s)