Comparative Study of 0.75% Ropivacaine alone with 0.75% Ropivacaine and Dexmedetomidine Epidurally for Lower Limb & Lower Abdominal Surgery
Keywords:
Epidural Anaesthesia, Ropivacaine, DexmedetomidineAbstract
Neuraxial adjuvants are used with local anaesthetic agents to enhance the quality of anaesthesia. The present study aimed at comparing the efficacy & safety of adding á2- adrenergic agonist, DEXMEDETOMIDINE to 0.75% Ropivacaine with Ropivacaine alone epidurally for lower limb & lower abdominal surgery. It was concluded that addition of Dexmedetomidine to local anaesthetic agent Ropivacaine 0.75% epidurally as an adjuvant provides better sensory and motor block, intraoperative sedation and prolonged postoperative analgesia.
Downloads
References
McClure JH.Ropivacaine.Br JAnaesth 1996;76:300-307.
Tucker GT.Ropivacaine: Human pharmacokinetics. Am J Anaesthesiol 1997;24 (5;suppl):8-13.
Khangure, N 2011,Adjuvant Agents In NeuraxialBlockade,King Edwards Memorial Hospital for Women, viewed 26 september 2012, <http://totw.anaesthesiologists . o rg / w p - c o n te n t / . . . / 2 3 0 - N e u ra x i a l - adjuvants >.
Brandão ST, Mauro VA, Aguiar BA, Tonante LM. Intra-operativeanalgesic effect of ketamine, clonidine and dexmedetomidine, administered through epidural route in surgery of the upperabdomen. Rev Bras Anestesiol 2005;55:5,525-231.
Breen, T.W., et al. Modified Bromage Scale. AnesthAnalg, 1993. 77(5): p. 919-24.
Hall JE, Uhrich TD, et al. Sedative, amnestic and analgesic properties of small-dose Dex infusions. AnesthAnalg 2000;90:699-705.
Oriol-López SA et al. Epidural dexmedetomidine in regional anesthesia. Revista Mexicana de Anestesiologia 2008;31:272- 274.
Salgado PF, Sabbag AT, Silva PC, Brienze SL, Dalto HP, Módolo NS, Braz JR, Nascimento P Jr Synergistic effect between dexmedetomidine and 0.75% ropivacaine in epidural anesthesia. Rev Assoc Med Bras. 2008 MarApr;54(2):110-5.
Bajwa S, Arora V, Kaur J, Singh A, Parmar SS. Comparative evaluation of dexmedetomidine and fentanyl for epidural analgesia in lower limb orthopedic surgeries. Saudi J Anaesth 2011;5:365-70.
Mauro VA, Brandão ST, et al. Clonidine and dexmedetomidine through epidural route for post-operative analgesia and sedation in a colecistectomy. Rev Bras Anestesiol 2004;4:1-10.
Jain D, et al. Perioperative effect of epidural dexmedomidine with inthrathecal bupivacaine on haemodynamic parameters and quality of analgesia. Southern African Journal
