A Randomized Comparative Study of Attenuation of The Pressure Response and Ease of Insertion to Awake Fibreoptic Intubation with Dexmedtomidine Infusion Alone Vs Fentanyl and Midazolam Infusion
Keywords:
Awake, Fibreoptic, Intubation, Dexmedtomidine, Fentanyl, MidazolamAbstract
When performing awake fibreoptic intubation, anesthesiologists may find it difficult to provide enough sedation for patient to be comfortable and cooperative one at the same time avoiding airway compromise from too much sedation. The ideal sedation provides patient comfort and maintenance of spontaneous respiration smooth intubation conditions amnesia and stable hemodynamic.
Downloads
References
Grant SA, Breslin DS, Macleod DB, Gleason D, Martin G.Dexmedetomidine infusion for sedation during fiberoptic intubation: a report of three cases.J Clin Anesth. 2004 Mar;16(2):124-6.
Hall JE1, Uhrich TD, Barney JA, Arain SR, Ebert TJ.Sedative, amnestic, and analgesic properties of smalldose dexmedetomidine infusions.Anesth Analg. 2000 Mar;90(3):699-705.
Kamibayashi T1, Maze M.Clinical uses of alpha2 - adrenergic agonists.Anesthesiology. 2000 Nov;93(5):1345-9.
RM,Bradshaw CJ, Spencer R,etal . Prelimimary UK experience of dexmedtomidine , a novel agent fpr post op sedation in intensive care unit .Anaesthesia 1999:54:1136-42
Ambuel B, Hamlett KW, Marx CM,Blumer JL. Assessing distress in pediatric intensive care. the COMFORT scale. J Pediatr Psychol. 1992;17(1):95-109
Jain V, Chandak A, Ghosh A, Golhar M.Comparison of dexmedetomidine and fentanyl for attenuation of the hemodynamic response to laryngoscopy and tracheal intubation.Ain- Shams J Anaesthesiol 2015;8:236-43
Mondal S, Ghosh S, Bhattacharya S, Choudhury B, Mallick S, Prasad A. Comparison between dexmedetomidine and fentanyl on intubation conditions during awake fiberoptic bronchoscopy: A randomized double-blind prospective study. J Anaesthesiol Clin Pharmacol 2015;31:212-6
Kharwar DRK, Kumar DM, Tiwary DPK, Suwalka DU, P r a k a s h D . A C o m p a r i s o n O f I n t r a v e n o u s Dexmedetomidine V/S Inj. Fentanyl For Attenuation Of Hemodynamic Responses During Laryngoscopy And Intubation After Propofol Induction. NJIRM. 2014; 5(3): 71-75
Gandhi S, Goyal V, Radhakrishnan K, Balakrishnan M. Comparison of Dexmedetomidine with fentanyl in attenuation of pressor responses during laryngoscopy and intubation. IOSR Journal of Pharmacy.2014;4(2):28-38
Tsai CJ, Chu KS, Chen TI, Lu DV, Wang HM, Lu IC. A comparison of the effectiveness of dexmedetomidine versus propofol target-controlled infusion for sedation during fibreoptic nasotracheal intubation. Anaesthesia 2010;65:254-9
Bloor BC, Ward DS, Belleville JP,Maze M. Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology. 1992;77(6):1134-42.
Talke P, Richardson CA, Scheinin M,Fisher DM. Postoperative pharmacokinetics and sympatholytic effects of dexmedetomidine. Anesth Analg. 1997;85(5):1136-42.
Gupta K, Maggo A, Jain M, Gupta PK, Rastogi B, Singhal AB. Blood glucose estimation as an indirect assessment of modulation of neuroendocrine stress response by dexmedetomidine versus fentanyl premedication during laparoscopic cholecystectomy: A clinical study. Anesthesiol Clin Pharmacol.2015;31(2):212-216
Cattano D1, Lam NC, Ferrario L, Seitan C, Vahdat K, Wilcox DW, Hagberg CA.Dexmedetomidine versus Remifentanil for Sedation during Awake Fiberoptic Intubation. Anesthesiol Res Pract. 2012;2012:753107
Patrick BS, Sergio D, Thomas D, Soleded F,Roger D. A comparative study of dexmedetomidine with midazolam and midazolam alone for sedation during elective awake fiberoptic intubation.Journal of clinical anaesthesia. 2010;22:35-40
Bergese SD, Khabiri B, Roberts WD, Howie MB, McSweeney TD, Gerhardt MA. Dexmedetomidine for conscious sedation in difficult awake fiberoptic intubation cases. J Clin Anesth 2007;19:141-4.
Stuart AG, Dara SB,David BM,David G, Gavin M. Dexmedetomidine infusion for sedation during fibreoptic intubation:a report of three cases. J Clin Anesth.2003;16(2):124-126
Hall JE, Uhrich TD, Barney JA, Arain SR, Ebert TJ. Sedative, amnestic, and analgesic properties of small-dose dexmedetomidine infusions. Anesth Analg 2000;90:699- 705.
Agrawal A, Jadon A, Parida SS, Chakraborty S, Sinha N,Chandra O. Comparative evaluation of Dexmedetomidine and Fentanyl – Midazolam combination as sedative adjunct to fibreoptic intubation under topical anaesthesia. American Journal of Advances in Medical Sciences.2014;2(4):29-37.
Ryu JH, Lee SW, Lee JH, Lee EH, Do SH, Kim CS. Randomized double-blind study of remifentanil and dexmedetomidine for flexible bronchoscopy. Br J Anaesth 2012;108:503-11.
Bailey PL, Pace NL, Ashburn MA, Moll JW, East KA, Stanley TH. Frequent hypoxemia and apnea after sedation with midazolam and fentanyl. Anesthesiology 1990; 73:826-30.
Chu KS, Wang FY, Hsu HT, Lu IC, Wang HM, Tsai CJ. The effectiveness of dexmedetomidine infusion for sedating oral cancer patients undergoing awake fibreoptic nasal intubation. Eur J Anaesthesiol 2010;27:36-40
Bergese SD, Candiotti KA, Bokesch PM, Zura A, Wisemandle W,Bekker AY. A Phase IIIb, randomized, double-blind, placebo-controlled, multicenter study evaluating the safety and efficacy of dexmedetomidine for sedation during awake fiberoptic intubation. Am J Ther. 2010; 17(6):586-95.