TO COMPARE THE DELINEATION OF FETAL BRAIN LAMINATION BETWEEN T2-WEIGHTED SINGLE-SHOT FAST SPIN ECHO AND ECHO PLANAR IMAGING FLUID ATTENUATED INVERSION RECOVERY IMAGES
Keywords:
FLAIR, SSFSE, Fetal Brain lamination, Hypoxic inschemic injuryAbstract
The human cerebrum undergoes age-specific lamination changes during development. Notably, the subplate zone stands out as the most significant transient area, where major afferent systems temporarily settle, form synapses, and engage in essential cellular interactions critical for future cortical development. Our research utilized magnetic resonance imaging (MRI) to track the developmental history of this key cortical layer (the subplate zone) and other laminar regions of the fetal cerebral wall from 26 to 32 weeks post-ovulation. The study revealed that alterations in the MRI lamination pattern of the fetal cerebral wall are largely attributed to changes in the subplate zone. This zone is vital for creating important connections between the thalamus and cortex, coinciding with the period when the cortical mantle starts forming sulci and gyri. The present study was conducted on 50 patients and focused on the comparison of fetal brain lamination (Subplate) between T2-weighted SSFSE and EPI-FLAIR sequences to help guide the decision on the utilization of neuroimaging in the diagnostic workup referred to the Radiodiagnosis Department in Government Rajindra Hospital, Patiala.
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