Study of Ondansetron and Dexmedetomidine to Prevent Post-op Nausea and Vomiting in Patients Undergoing Laparoscopic Cholecystectomy Under General Anaesthesia
Keywords:
post-op nausea and vomiting, I/v dexmedetomidine, I/v ondansetron, laparoscopic cholecystectomy, general anaesthesiaAbstract
Introduction Post-operative nausea and vomiting is one of the most distressing problems faced by the anaesthesiologists worldwide which causes unpleasant side effects, delayed discharge and delayed wound healing. Aim To compare the efficacy of ondansetron with dexmedetomidine to prevent post operative nausea and vomiting. Materials and Method This randomised clinical trial study was performed on patients who were candidates for laparoscopic cholecystectomy referring to St. Stephens hospital in New Delhi. In this study, 60 patients with laparoscopic cholecystectomy were randomly assigned to two groups (ondansetron and dexmedetomidine). Results We found that total incidence of PONV in 24 hours was 46.7% in Dexmedetomidine group and 30% in Ondansetron group. No significant side effects were noted by the use of the two drugs. Conclusion We concluded that the use of both Ondansetron and Dexmedetomidine is recommended for ameliorating PONV. In terms of efficacy, both the drugs are equally effective in reducing the incidence of PONV.
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References
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