Microbiological and Antimicrobial Resistance profile of isolates from Surgical Site Infections: a study in a Tertiary Care Hospital
Keywords:
Wound Infections, Surgical Site infections, Hospitals, Bacterial profile, Antibiotic drug resistanceAbstract
Post-operative wound infections or surgical site infections (SSIs) cause critical healthrelated infections resulting in longer hospital stays, increased healthcare expenses, patient’s discomfort and are likely to have an important role in the growth of antimicrobial resistance. Staphylococcus is the most common bacterial organism causing wound infections in hospitals. The present study was done to identify aerobic cultural isolates from post-operative infected wounds and to study the drug susceptibility profile of the bacterial isolates. Staphylococcus aureuswere the most commonly isolated bacteria followed byE. coli, K. pneumonia, Pseudomonas aeruginosa, Proteusmirabilis, and Acinetobacterbaumanii complex. The drug resistance susceptibility profile showed high rate of drug resistance to most commonly used drugs like gentamicin, ciprofloxacin and ceftriaxone.
Downloads
References
Skov RL, Jensen KS. Community-associated meticillin-resistant Staphylococcus aureus as a cause of hospital-acquired infections. J Hosp Infect2009;73(4):364-370.
Wanjare VS, Wanjare SW, Rahule AS, Mahato LO, Balvir TKA. Study of Postoperative Wounds Infections with Special Reference to Staphylococcus Aureus-A Study in a Tertiary Care Centre of Vidarbha Region of India. J Cont Med A Dent 2014;2:17-21.
Araujo BF, Ferreira ML, Campos PAD, Royer S,Batistão DWDF,Dantas RCC,RibasRM. Clinical and Molecular Epidemiology of MultidrugResistant P aeruginosa carrying aac (6')-Ib-cr qnrS1 and bla SPM Genes in Brazil. PloS one 2016;11(5):e0155914.
Li B, Webster TJ. (2018) Bacteria antibiotic resistance: New challenges and opportunities for implant associated orthopedic infections Journal of Orthopaedic Research J Orthop Res 2018;36(1):22-32.
Jain K,Chavan NS, Jain SM. Bacteriological profile of post-surgical wound infection along with special reference to MRSA in central India Indore Int J Intg Med Sci 2014;1(1):9-13.
Bhattacharya S, Pal K, Jain S,Chatterjee SS, Konar J. Surgical site infection by methicillin resistant staphylococcus aureus–On decline? J ClinDiagn Res 2016;10(9):DC32-DC36.
Sankar N, NazeerM HA, Moinuddin K. Spectrum of surgical site infections with special reference to methicillin resistant Staphylococcus aureus (MRSA).Int J SurgSci 2020;4(2):306-309.
MJ, Munyaneza E, Muhawenayo E, Nyirasebura D, Abahuje E, Nyirigira J, Harelimana JD, Muvunyi TZ, Masaisa F, Byiringiro JC, Hategekimana T. Incidence, root causes, and outcomes of surgical site infections in a tertiary care hospital in Rwanda: a prospective observational cohort study. Patient safety in surgery 2019;13(1):1-8
Manyahi J, Matee MI, Majigo M, Moyo S, Mshana SE, Lyamuya EF. Predominance of multi-drug resistant bacterial pathogens causing surgical site infections in Muhimbili National Hospital, Tanzania. BMC research notes 2014;7(1):1-7.
Amare B, Abdurrahman Z, Moges B, Ali J, Muluken L, Alemayehu M, Yifru S, Sendek B, Belyhun Y, Moges F, Kassu A. Postoperative surgical site bacterial infections and drug susceptibility patterns at Gondar University Teaching Hospital, Northwest Ethiopia. J Bacteriol Parasitol 2011;2(8):126.
National Nosocomial Infections Surveillance (NNIS) System National Nosocomial Infections Surveillance (NNIS) report data summary from October 1986 April 1996 issued May Am J Infect Control 1996;24(5):380-388
Negi V, Pal S, Juyal D, Sharma MK, Sharma N. Bacteriological profile of surgical site infections and their antibiogram: A study from resource constrained rural setting of Uttarakhand state India J ClinDiagn Res 2015;9(10): DC17-DC20.
Yehouenou CL, Kpangon AA, Affolabi D, Rodriguez-Villalobos H, Van Bambeke F, Dalleur O, Simon A. Antimicrobial resistance in hospitalized surgical patients: a silently emerging public health concern in Benin. Annals of clinical microbiology and antimicrobials 2020;19(1):54.
Chaudhary R, Thapa SK, Rana JC, Shah PK. Surgical site infections and antimicrobial resistance pattern. Journal of Nepal Health Research Council 2017;15(2):120-123
Mehrad B, Clark NM, Zhanel GG, Lynch IIIJP. Antimicrobial resistance in hospital-acquired gram-negative bacterial infections. Chest 2015;147(5):1413-1421
Nichols RL. Preventing surgical site infections: a surgeon's perspective. Emerg Infect Dis 2001;7(2):220-224.
Savage TJ, Rao S, Joerger J, Ozonoff A, McAdam AJ, Sandora TJ. Predictive value of direct disk diffusion testing from positive blood cultures in a children’s hospital and its utility in antimicrobial stewardship. Journal of clinical microbiology 2021 19;59(6):e02445-20.
Ali Q, Siddique K, Mirza S, Malik A. Comparison of superficial surgical site infection following use of diathermyand scalpel for making skin incision in inguinal hernioplasty. Niger J ClinPract2009;12(4):371-374
Barie PS. Surgical site infections: epidemiology and prevention. Surg Infect (Larchmt) 2002; 3(S1):s9-s21.20. Nichols RL. Surgical infections: prevention and treatment—1965 to 1995. Am J Surg 1996; 172(1):68-74.