Role of Bronchoscopy in the Diagnosis of Pulmonary Tuberculosis in Sputum Smear Negative Patients

Authors

  • Vishal Chopra Associate Professor Deptt. Of Chest & TB(Pulmonary Medicine) Govt. Medical College Patiala.
  • Chahal AS Medical Officer; Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India.
  • Jain H Junior Resident; Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India.
  • Joshi JL Assistant Professor; , Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India.
  • Singh V Junior Resident, Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India
  • Ramaraj M. Junior Resident; Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India.
  • Bansal AK Junior Resident; Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India.
  • Singh UP Professor; Dept. of Pulmonary Medicine, Govt. Medical College, Patiala, Punjab, India.

Keywords:

Fiberoptic Bronchoscopy, Smear negative Tuberculosis

Abstract

Around 30% of cases of pulmonary TB are sputum smear negative. Bronchoscopy can be a useful adjunctive technique to diagnose TB in such cases. Of the 114 smear negative patients who underwent bronchoscopy, 28 (24.56%) were turned to be smear positive. Of these, 6 (5.26%) were positive for AFB on post FOB sputum examination alone, 4 (3.50%) were positive on BAL examination alone, while 18 (15.79%) were positive with both these samples. The results of the study suggest that bronchoscopy is a useful diagnostic technique and should be performed, wherever possible, in all smear negative patients to avoid delay in diagnosing the disease and initiating treatment, thus effectively reducing its transmission to the community.

Downloads

Download data is not yet available.

References

Narain JP. Tuberculosis Epidemiology and Control. New Delhi: WHO regional office for South East Asia; 2001.

R o b e r t s G D . B a c t e r i o l o g y a n d bacteriological diagnosis of tuberculosis in David Schlosberg ed. Tuberculosis. 2nd ed. New York: Springer Verlag Publishing Company; 1988

Choudhary S, Tayade BO, Kharbade S, Sontakke A, Khan S, Abraham R. Outcome of fiber optic bronchoscopy in sputum smear negative pulmonary tuberculosis. Panacea J Med Sci 2015;5:33–9

Harries A D, Maher D NP. An approach to the problems of diagnosing and treating adult smear-negative pulmonary tuberculosis in high HIV-prevalence settings in sub-Saharan Africa. Bull World Heal Organ 1998;76:651–662.

Kumar R, Singh M, Gupta N, Goel N. Bronchoscopy in immediate diagnosis of smear negative tuberculosis. Pneumonol Alergol Pol 2014;82:410–4. doi:10.5603/ PiAP.2014.0053.

Mohan A, Sharma SK. Fibreoptic bronchoscopy in the diagnosis of sputum smear-negative pulmonary tuberculosis: current status. Indian J Chest Dis Allied Sci 2008;50:67–78

Shin JA, Chang YS, Kim TH, Kim HJ, Ahn CM, Byun MK. Fiberoptic bronchoscopy for the rapid diagnosis of smear-negative pulmonary tuberculosis. BMC Infect Dis 2012;12:1. doi:10.1186/1471-2334-12- 141.

Elston WJ, Whittaker AJ, Khan LN, FloodPage P, Ramsay C, Jeffery PK, et al. Safety of research bronchoscopy, biopsy and bronchoalveolar lavage in asthma. Eur Respir J 2004;24:375–7. doi:10.1183 /09031936.04.00063003.

Quaiser S, Agarwal A, Khan R, Haque SF. Fiberoptic bronchoscopy, as a valuable diagnostic option in sputum negative pulmonary tuberculosis: A prospective study. Int J Appl Basic Med Res 2012;2:123–7. doi:10.4103/2229-516X. 106355.

Singhal S, Gaidhane AM, Khatib N, Srivatsava T, Diwan S, Mahajan SN, et al. Use of flexible bronchoscopy for rapid diagnosis of suspected tubercular cases in rural India. J Infect Dev Ctries 2009;3: 860–4.

Soto A, Salazar D, Acurio V, Segura P, Van der Stuyft P. Evaluation of the diagnostic utility of fiberoptic bronchoscopy for smear-negative pulmonary tuberculosis in routine clinical practice. J Bras Pneumol Publicaça?o Of Da Soc Bras Pneumol E Tisilogia 2012;38:757–60.

Iyer VN, Joshi AY, Boyce TG, Brutinel MW, Scalcini MC, Wilson JW, et al. Bronchoscopy in suspected pulmonary TB with negative induced-sputum smear and MTD?? Gen-probe testing. Respir Med 2011;105:1084–90. doi:10.1016/j.rmed. 2011.03.003.

Downloads

Published

30-06-2018

How to Cite

Vishal Chopra, Chahal AS, Jain H, Joshi JL, Singh V, Ramaraj M., Bansal AK, & Singh UP. (2018). Role of Bronchoscopy in the Diagnosis of Pulmonary Tuberculosis in Sputum Smear Negative Patients. GMC Patiala Journal of Research and Medical Education, 1(1), 42–44. Retrieved from https://jrme.gmcpatiala.edu.in/index.php/j/article/view/8

Issue

Section

Original Research Articles