Massive Transfusion and Blood Product Dynamics in Obstetric Hysterectomy: A One-Year Prospective Study from a Tertiary Care Centre in North India
Keywords:
Massive transfusion, Obstetric hysterectomy, Post partum hemorrhage, Placenta accreta, Blood transfusion practiceAbstract
Obstetric hysterectomy (OH) is a maternal near-miss event most often required for catastrophic obstetric hemorrhage, with blood transfusion being unavoidable. This prospective observational study conducted over one year (February 2023–January 2024) at a
tertiary care center in North India evaluated blood and blood product utilization and maternal outcomes in women undergoing OH. Among 3,759 deliveries, 37 women underwent OH (incidence 9.84/1,000), with placenta accreta spectrum being the leading indication (64.8%). All patients required packed red blood cell transfusion (mean 4–6 units), while fresh frozen plasma, platelets, and cryoprecipitate were used in 50%, 20%, and 6.6% of cases, respectively. Maternal deaths occurred only in cases requiring massive transfusion (>10 PRBC units), predominantly associated with PAS. The study emphasizes that optimal transfusion support, early activation of massive transfusion protocols, and blood bank preparedness are critical for improving outcomes in obstetric hysterectomy, especially in resource-limited settings.
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Copyright (c) 2026 Verma K, Kaur SP, Kaur P
This work is licensed under a Creative Commons Attribution 4.0 International License.
