ANTIMICROBIAL PROFILES ANTIMICROBIAL PROFILES OF UROPATHOGENS IN A TERTIARY CARE HOSPITAL OF NORTHWESTERN INDIA
ANTIMICROBIAL PROFILES OF UROPATHOGENS
Keywords:
Antibiotic resistance; Urinary tract infections; Uropathogens; gram negative;gram positive; Healthcare-associated infectionsAbstract
Background: Urinary tract infections (UTIs) are extensively studied due to their high prevalence and potential severity, particularly concerning antimicrobial properties.. This study evaluated the prevalence of common uropathogens and their antimicrobial resistance.
Method: A prospective cross-sectional study was conducted on a total of 16,077 urine samples at a tertiary care hospital in Patiala, Punjab, from January 2022 to December 2022, using standardized microbiological methods. The isolated microorganisms underwent antibiotic resistance testing using the Kirby-Bauer disk diffusion method.
Results: A total of 16,077 urine samples were analyzed among Gram-negative microorganism Esch. coli (n=1962) was the most prevalent microorganism, followed by Klebsiella pneumoniae (n=722), Pseudomonas aeruginosa (n=572), Acinetobacter Baumanni Complex(451), Citrobacter species (n=132), Proteus spp. (n=96), and Enterobacter spp. (n=12). Among Gram positive Enterococcus spp. (n=786) was most prevalent, followed by Staphylococcus aureus (n=420), and MRSA (n=30); antibiotic profile data revealed that Gram-negative have high resistance rates towards Ampicillin, Ciprofloxacin, and Amoxicillin-clavulanate and among gram-positive resistance rate was higher in Ampicillin, CiprofloxacinAmoxicillin-clavulanate, Gentamicin, Levofloxacin, Erythromycin, and Netilmicin.
Conclusion: Esch. coli and Enterococcus spp. emerged as the predominant uropathogen, exhibiting high antibiotic resistance against various antibiotics.
Keywords: Antibiotic resistance; Urinary tract infections; Uropathogens; gram negative;gram positive; Healthcare-associated infections
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References
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